Comentario de The Perth Group:
En el único estudio EM (Microscopía Electrónica), ya sea in vivo o in vitro, en el que se utilizaron los controles adecuados y en el que se realizó un amplio examen-ciego de los controles y material de ensayo, se encontraron partículas de virus indistinguibles del “VIH” en 18/20 (90%) de los pacientes con SIDA , así como en 13/15 (88%) de los no-SIDA o de ningún riesgo de SIDA, en las ampliaciones de ganglios linfáticos. Esto llevó a los autores a concluir: “La presencia de tales partículas no indica, por sí mismas, una infección por el VIH”.
¿Se puede distinguir el paciente de SIDA del paciente sin SIDA?
Así pues, la respuesta a la pregunta “¿Qué hemos estado buscando en todos estos años?” debería reformularse “¿Qué hemos estado mirando y no mirando todos estos años?” [11]. Cualquiera que sea la respuesta, puede ser presuntuoso afirmar que es un retrovirus.
El estudio:
- PMID:3371979 [PubMed – indexed for MEDLINE]
- The ultrastructural and immunohistochemical demonstration of viral particles in lymph nodes from human immunodeficiency virus-related and non-human immunodeficiency virus-related lymphadenopathy syndromes. O’Hara CJ, Groopman JE, Federman M. Department of Pathology, England Deaconess Hospital, Harvard Medical School, Boston, MA 02215.
Abstract
Viral particles have been demonstrated by electron microscopy in lymph nodes from patients with acquired immune deficiency syndrome AIDS-related persistent generalized lymphadenopathy (PGL) syndrome. Immunohistochemical and in situ hybridization studies have identified these viruses as the human immunodeficiency virus (HIV). In this study, we examined 20 PGL lymph nodes and found viral particles in 18 cases. Immunohistochemical studies on these cases revealed positive staining for the HIV core protein P24 within germinal centers of secondary follicles. In addition we found viral particles, morphologically indistinguishable from those observed in PGL lymph nodes, in 13 of 15 non-HIV related reactive lymph nodes. Immunohistochemical staining of these lymph nodes for the P24 core protein was negative. None of the patients in this group had risk factors for developing AIDS and none exhibited clinical evidence of immune deficiency. We conclude that the viral particles observed in PGL lymph nodes are most likely HIV, but similar particles can be seen in reactive lymph nodes not associated with HIV infection. The discrete localization of these particles within germinal centers has been observed for other viruses and immune complexes and a possible mechanism of this antigen deposition is discussed.
Disiciencia 